HyCyte® | 海星生物

Positive WB detected in：HeLa cells

Positive IP detected in：——

Positive IHC detected in：——

Positive IF/ICC detected in：HeLa cells

Positive FC (Intra) detected in：——

推荐稀释比：应用 推荐稀释比

Western Blot (WB) WB : 1:500-1:2000

Immunofluorescence (IF)/ICC IF/ICC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

文献引用反应性：

免疫原：CatNo: Ag12757

Product name: Recombinant human ABCD1 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 358-745 aa of BC025358

Sequence: SESDAEAVKKAALEKKEEELVSERTEAFTIARNLLTAAADAIERIMSSYKEVTELAGYTARVHEMFQVFEDVQRCHFKRPRELEDAQAGSGTIGRSGVRVEGPLKIRGQVVDVEQGIICENIPIVTPSGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTYGGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSVEDMQRKGYSEQDLEAILDVVHLHHILQREGGWEAMCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIPKMQRRLQELCQILGEAVAPAHVPAPSPQGPGGLQGAST

抗体类别：Monoclonal

产品类型：Antibody

全称：ATP-binding cassette, sub-family D (ALD), member 1

计算分子量：745 aa, 83 kDa

观测分子量：75 kDa

GenBank蛋白编号：BC025358

基因名称：ABCD1

Gene ID (NCBI)：215

RRID：AB_10640436

偶联类型：Unconjugated

形式：Liquid

纯化方式：Protein G purification

UNIPROT ID：P33897

储存缓冲液：PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.

储存条件：Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍：ABCD1 (also known as ALDP) is a member of the ATP-binding cassette (ABC) transporter superfamily which functions as transporter for a wide variety of substrates. It localizes to the peroxisomal membrane. The exact function is not clear so far. Various mutations of ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), an inherited neurodegenerative disease affecting the nervous system white matter and adrenal cortex.

注意事项

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗等用途。

2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。