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基因编辑服务发表部分文章

1. Cas9X^®永生化小鼠骨髓源巨噬细胞（iBMDM）基因敲除：影响因子为52.7

Xu Y, Zheng Y, Liu Y, Wei C, Ren J, Zuo W, Gu R, Liu H, Deng X, Liu Y, Shang X, Ge W, Li Z, Huang Y, He D, Shen X, Wang Z, Lyu C, Wang Z, Mu Y, Zhang Z, Wu H, Li H, Cao B. Ninjurin-1 mediates cell lysis and detrimental inflammation of PANoptosis during influenza A virus infection. Signal Transduct Target Ther. 2025 Sep 23;10(1):307. doi: 10.1038/s41392-025-02391-9.

2. Cas9X^®基因编辑服务：影响因子为23.65

Wu W, Pu Y, Gao S, et al. Bacterial Metabolism-Initiated Nanocatalytic Tumor Immunotherapy[J]. Nano-Micro Letters, 2022, 14(1): 1-21.

3. Cas9X^®基因编辑服务：影响因子为17.694

Bu, J., Zhang, Y., Wu, S. et al. KK-LC-1 as a therapeutic target to eliminate ALDH+ stem cells in triple negative breast cancer. Nat Commun 14, 2602 (2023).

4. Cas9X^®基因编辑服务：影响因子为8.322

Li W, Ali T, Zheng C, et al. Fluoxetine regulates eEF2 activity (phosphorylation) via HDAC1 inhibitory mechanism in an LPS-induced mouse model of depression[J]. Journal of neuroinflammation, 2021, 18(1): 1-19.

5. Cas9X^®基因编辑服务：影响因子为15.992

Li W, Ali T, Zheng C, et al. Anti-depressive-like behaviors of APN KO mice involve Trkb/BDNF signaling related neuroinflammatory changes[J]. Molecular Psychiatry, 2022, 27(2): 1047-1058.

6. Cas9X^®基因编辑服务：影响因子为5.59

Xiao P, Chen J, Zeng Q, et al. UNC5B Overexpression Alleviates Peripheral Neuropathic Pain by Stimulating Netrin-1-Dependent Autophagic Flux in Schwann Cells[J]. Molecular Neurobiology, 2022: 1-15.

7. Cas9X^®基因载体服务：影响因子为3.9

Kang J, Abudurufu M, Zhang S, et al. lncRNA VIM-AS1 acts as a prognostic biomarker and promotes apoptosis in lung adenocarcinoma[J]. Journal of Cancer, 2023, 14(8): 1417.

8. Cas9X^®基因编辑服务：影响因子为38.12

Ma B, Ju A, Zhang S, et al. Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease[J]. Signal Transduction and Targeted Therapy, 2023, 8(1): 229.

9. THP1细胞基因突变：影响因子为14.7

Liang J, Wan Y, Gao J, et al. Erythroid-intrinsic activation of TLR8 impairs erythropoiesis in inherited anemia[J]. Nature Communications, 2024, 15(1): 1-17.

10. CRlSPR-Cas9：影响因子为14.3

Jia S, Liu W, Zhang M, Wang L, Ren C, Feng C, Zhang T, Lv H, Hou Z, Zou W, Zhang Y, Tong W, Wang J, Chen W. Insufficient Mechanical Loading Downregulates Piezo1 in Chondrocytes and Impairs Fracture Healing Through ApoE-Induced Senescence. Adv Sci (Weinh). 2024 Oct 17:e2400502.

11. Cas9X^®基因干扰siRNA：影响因子为9.1

Bian Y, Xu S, Gao Z, Ding J, Li C, Cui Z, Sun H, Li J, Pu J, Wang K. m6A modification of lncRNA ABHD11-AS1 promotes colorectal cancer progression and inhibits ferroptosis through TRIM21/IGF2BP2/ FOXM1 positive feedback loop. Cancer Lett. 2024 Aug 1;596:217004.

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