The 786-O [786-0] cell line is derived from a primary clear cell carcinoma; the 786-O [786-0] cells possess microvilli and desmosomes, and are capable of growing in soft agar. The 786-O [786-0] cells produce a PTH-like polypeptide that is similar to peptides found in breast and lung cancers. The N-terminal of this polypeptide is similar to that of PTH, its activity is also similar to PTH, and its molecular weight is 6,000 daltons.

Cell Name: Human renal cell adenocarcinoma cell line (STR authenticated)
Cell Synonyms: 786-O; 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT

Catalogue No.: TCH-C107
Species: Human
Tissue Origin: Kidney
Disease Characteristics: Renal Cell Adenocarcinoma

Morphology:Epithelial-like
Growth Properties: Adherent

Culture Medium: RPMI-1640 + 10% FBS+ 1% P/S
Matching Medium Catalog Number: TCH-G107

Passage Ratio: 1:3-1:4, with medium renewal every 2-3 days
Doubling Time: 24-48 h
Culture Conditions: Atmosphere: 95% air + 5% CO₂, Temperature: 37°C

Freezing Conditions: 60% basal medium + 30% FBS + 10% DMSO, stored in liquid nitrogen

Recommended HyCyte® One-Step Cryopreservation Medium (ready-to-use, serum-free, no programmed cooling required), Product No.: GUCP-R201
Quality Control: Negative for bacteria, fungi, and mycoplasma detection